The enthalpies of l-glutamine dissolution in an aqueous solution of acetamide, N-methylacetamide, and N, N-dimethylacetamide were determined by the calorimetric method at T = 298.15 K and organic solvent mole fractions up to x2 ~ 0.25. The standard enthalpies of solution (ΔsolH°) and transfer (ΔtrH°) of l-glutamine from water to a mixed solvent as well as the enthalpy coefficients of pairwise interactions (hxy) were calculated. The interrelation between enthalpic characteristics of l-glutamine dissolution (transfer) and the composition of water-organic mixtures was determined. The received thermochemical characteristics of intermolecular interactions of l-glutamine with the molecules of acetamides were compared with the analogous characteristics interactions of l-glutamine with the molecules of formamides (formamide, N-methyformamide, and N, N-dimethylformamide).
