The saturated vapor pressure of sotalol and ivabradine hydrochlorides was measured in the temperature range (413.15–437.15) K by the transpiration method. The sublimation thermodynamic functions (Gibbs energy, enthalpy and entropy) of the compounds were calculated from the temperature dependencies of saturated vapor pressure. The standard molar enthalpy of sublimation for sotalol and ivabradine hydrochlorides is (157.5 ± 1.4) kJ·mol−1 and (143.2 ± 1.2) kJ·mol−1, respectively. The thermal properties and crystal state of the drugs were studied by the DSC, TG/DTG and X-ray diffraction methods.
