Ol’khovich Marina Vasilyevna

Position: 
Researcher
Degree: 
Phd in chemistry
Phone: 
+7 (4932) 351545
E-mail: 
oad@yandex.ru
Subdivision: 
Laboratory of physical chemistry of drug compounds
Awards and honors:

Diploma of the Presidium of RAS and RAS Trade Union.

Research interests:
  1. Solubility, thermodynamics of solution and solvation of molecular crystals of drug compounds and their analogs in organic solvents, water and buffer solutions
  2.  Distribution processes of drug compounds in biological mediums.
  3.  Thermodynamics of sublimation of molecular crystals of drugs.
Participation in grants and programs:
  • The Russian Foundation for Basic Research
  • The Russian Scientific Foundation (№ 14-13-00640)
  • The Federal Agency for Science and Innovations (№ 02.740.11.0857; № 14.616.21.0027)
The most important publications:
  1. S.V. Blokhina, N.V. Usol’tseva, M.V. Ol’chovich, A.V. Sharapova. Thermodynamics of solution in liquid crystalline poly(propyleneimine) dendrimers by inverse gas chromatography. // J. of Chromatogr. 2008. V. 1215. P. 161 – 167.
  2. S.V. Blokhina, N.V. Usol’tseva, M.V. Ol’chovich, A.V. Sharapova. Thermodynamics of the interaction of liquid_crystalline polypropyleneimine dendrimer with low_molecular_weight compounds studied by reversed phase gas chromatography. Russian Chemical Bulletin, International Edition, 2008 ,57, 1.
  3.  S.V. Blokhina, N.V. Usol’tseva, M.V. Ol’chovich, A.V. Sharapova. S.V. Blokhina, N.V. Usol’tseva, M.V. Ol’chovich, A.V. Sharapova. Mesomorphism of thermotropic  poly(propyleneimine) dendrimers and phase equilibria in systems based on their basis. Polymer Science A. 2008, 50, 322.
  4. S.V. Blokhina, M. V. Ol’khovich, A. V. Sharapova. Highly Selective Gas Chromatographic Sorbents for Gas Chromatography based on Liquid Crystalline Complexes of Copper and Nickel. In: Compounds and Materials with Specific Properties. Eds. B.A. Howell, N. Lekishvili, G.E. Zaikov. Nova Publisher. 2008. ISBN: 978-1-60456-3435. P. 61-66.
  5. S.V. Blokhina, M.V. Ol’khovich, A.V. Sharapova. Activity coefficients of butanol isomers in liquid crystalline cholesteryl tridecylate according to data of inverse gas chromatography and tensiometry. Russian Journal of Physical Chemistry A. 2010, 84, 299.
  6. S.V. Blokhina, M.V. Ol’khovich, A. V. Sharapova, N.Yu. Borovkov. Thermodynamics of Sorption in the Binary Liquid Crystalline System Composed of the Poly-(propyleneimine) Dendrimer and p-n-Pentyloxy-p-cyanobyphenyl by Inverse Gas Chromatography. // J. Phys. Chem. B. 2010. V. 114. P. 7703–7709.
  7. S.V. Blokhina, M.V. Ol’khovich, A.V. Sharapova. A thermodynamic approach to the study of the selectivity of liquid crystal reentrant phases. Russian Journal of Physical Chemistry. 2011, 6, 1010-1015.
  8. S.V.Blokhina, M.V.Оl’khovich, A.V.Sharapova, N.Yu. Borovkov Liquid crystalline poly(propyleneimine) dendrimers G1–G4: a chromatographic study on the local ordering of the terminal groups  J. Chem. Eng. Data 2011 , 56, 4208–4216.
  9. S.V. Blokhina, M.V. Ol’khovich, A.V. Sharapova, A. N. Proshin, G. L. Perlovich Thermodynamics of Solubility Processes of Novel Drug-like Spiro-Derivatives in Model Biological Solutions J. Chem. Eng. Data 2012, 57, 1996−2003.
  10. Ol’khovich M.V., Sharapova A.V., Blokhina S.V., Perlovich G.L., Proshin A.N. Vapor Pressures and Sublimation Thermodynamic Parameters for Novel Drug-Like Spiro-Derivatives. J. Chem. Eng. Data (2012) dx.doi.org/10.1021/je300610y.
main stages of research and teaching:

1981 - 1986 - Research Engineer of Institute of Solution Chemistry

1989 – 2001 - Junior Research Worker of Institute of Solution Chemistry

2001 - Ph.D. (physical chemistry)

2001 – 2005 - Research Worker of the Institute of Solution Chemistry

2005 -present time - Senior Research Worker of the Institute of Solution Chemistry