Khodov Ilya A.

Position: 
Department head
Senior researcher
Degree: 
Doctor of physical and mathematical sciences
Academic title: 
professor
Senior Researcher
Phone: 
+7 (4932) 351869
Awards and honors:

2011 First prize, Section of theoretical and experimental chemistry of liquid-phase systems, VI Regional young scientist conference. Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russia.

2011 First prize, Section of the problems of solvation and complex formation in solutions, XI International Conference. Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russia.

2013 First prize, Section of theoretical and experimental chemistry of liquid-phase systems, VIII Regional young scientist conference. Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russia.

2013 Excellent report, Proceedings of the XVI International Youth Scientific School «Actual problems of magnetic resonance and its application)). Kazan (Volga region) Federal University, Kazan, Russia.

2015 Excellent report, VIII Scientific and Practical Conference with international participation "Supercritical Fluids (SCF): fundamentals, technology, innovation"

Zelenogradsk, Kaliningrad region, Russia

2016 - The grant from President of the Russian Federation The title of the project 2016-2017: Development of new strategies for monitoring and controlling the crystallization of flexible drug-like molecules by two-dimensional NMR spectroscopy

2017 - The fellowship from DAAD for realization of the personal project at Institute of Medical Physics and Biophysics für Medizinische Physik und Biophysik, Leipzig, Germany, under supervision of Prof. Dr. Daniel Huster. The title of project: “The interaction of small molecules with phospholipid membranes studied by 1H NOESY NMR under magic-angle spinning”

2018 - Governor's Award for the high level of scientific research demonstrated, Ivanovo region, Ivanovo.

2019 First prize, Section of theoretical and experimental chemistry of liquid-phase systems, XII Regional young scientist conference. Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russia.

About:

Education

2005-2010: Physicist (specialist), Department of Theoretical Physics, Mathematical and computer modeling,  Ivanovo State University, Ivanovo, Russia.

His research interests:

·         The conformational state of the small molecules of bioactive compounds in different solvents. The spatial structure of the flexible molecules in different solvents by one-and two-dimensional NOESY.

·         Suppression of spin diffusion in two-dimension nuclear Overhauser spectra.

·         Complex formation by NMR spectroscopy. The analysis of one-, two-dimensional NMR spectra, the measurement of the relaxation times, 2D DOSY to study the association of molecules in solution.

Participation in grants and programs:

Research assistant Marie-Curie research program: “BioSol: Solvent effects on physico-chemical properties of bioactive compounds: combination of theory with European Commission, REA - Research Executive Agency, Grant No 247500, Programme: FP7-PEOPLE-2009-IRSES Kiselev’s group

Head of Grant Grant of the President of the Russian Federation for state support of young Russian scientists - PhD “МК-9048.2016.3”

Head of Grant Grant of the President of the Russian Federation for state support of young Russian scientists - PhD “МК-1409.2019.3”

The most important publications:

Gamov, G.A., Khodov, I.A., Belov, K.V., Zavalishin, M.N., Kiselev, A.N., Usacheva, T.R., Sharnin, V.A. Spatial structure, thermodynamics and kinetics of formation of hydrazones derived from pyridoxal 5′-phosphate and 2-furoic, thiophene-2-carboxylic hydrazides in solution (2019) Journal of Molecular Liquids, 283, pp. 825-833.DOI: 10.1016/j.molliq.2019.03.125

Khodov, I.A. Accuracy of determination of self-diffusion coefficients in studies of porphyrin-based complexes by 2D DOSY (2017) Macroheterocycles, 10 (3), pp. 313-316. DOI: 10.6060/mhc170200k

Khodov, I.A., Maltceva, O.V., Klochkov, V.V., Koifman, O.I., Mamardashvili, N.Zh.
N-Confused porphyrins: Complexation and 1H NMR studies (2017) New Journal of Chemistry, 41 (16), pp. 7932-7937. DOI: 10.1039/c7nj01814b

Khodov, I.A., Kiselev, M.G., Efimov, S.V., Klochkov, V.V. Comment on "conformational analysis of small organic molecules using NOE and RDC data: A discussion of strychnine and α-methylene-γ-butyrolactone" (2016) Journal of Magnetic Resonance, 266, pp. 67-68. DOI: 10.1016/j.jmr.2016.02.009

Khodov, I.A., Efimov, S.V., Klochkov, V.V., Batista De Carvalho, L.A.E., Kiselev, M.G. The importance of suppressing spin diffusion effects in the accurate determination of the spatial structure of a flexible molecule by nuclear Overhauser effect spectroscopy (2016) Journal of Molecular Structure, 1106, pp. 373-381. DOI: 10.1016/j.molstruc.2015.10.055

See full list of publications:

http://orcid.org/0000-0003-2439-9290

main stages of research and teaching:

since 05.2014    Senior  Scientist, Institute of Physics, Kazan Federal University, Kazan, Russia. Project: “Spatial structure of small peptides in solution by two-dimensional NMR spectroscopy” Laboratory NMR-Structure (Group of Prof. Klochkov).
since 11.2018    Senior  Scientist, Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russia.Group of Prof. Mikhail G. Kiselev)
09.2017-12.2017    Visiting researcher at Institute of Medical Physics and Biophysics für Medizinische Physik und Biophysik work group: "Membranes" (Prof. Dr. Daniel Huster)

02.2011-11.2014    Research Associate, Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russia
05.2014-07.2014 Visiting researcher at Institute of Analytical Chemistry work group:
"Structural Analytics: Photochemical Systems and NMR" (Prof. Stefan Berger) Department of Chemistry & Mineralogy of the University of Leipzig, Leipzig, Germany
2010 – 2013 Ph.D. in Physical Chemistry. G. A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, Ivanovo, Russia Thesis: Spatial structure and conformational preference of small molecules in solution by 1D and 2D NOESY NMR spectroscopy. Supervisor: Prof. Alper G.A.
07.2012-08.2012 and 05.2014-11.2014    Visiting researcher, Max Planck Institute for Mathematics in the Sciences Major: Physics; Minor: Theoretical Physics, Mathematics and Computer Modeling (Prof. M. Fedorov and Dr. N. Georgi ), Leipzig, Germany.
12.2010-02.2011    Trainee researcher, Institute of Solution Chemistry, Russian Academy of Sciences, Ivanovo, Russia
2005 – 2010    Graduated from the Ivanovo State University, Ivanovo, Russian, June 2010 Major: Physics; Minor: Theoretical Physics, Mathematics and Computer Modeling (Group of Prof. Dr. Loginov E.K.) Thesis: Fourier and wavelet signal processing. Supervisor: Gur'yanov A.V